Invention Application
- Patent Title: Process for the preparation of polyethylene glycol bis amine
- Patent Title (中): 制备聚乙二醇双胺的方法
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Application No.: US10272399Application Date: 2002-10-15
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Publication No.: US20030149307A1Publication Date: 2003-08-07
- Inventor: Ton That Hai , Larry J. Markoski , David E. Pereira , Mark Nordhaus
- Applicant: Baxter International Inc.
- Applicant Address: null
- Assignee: Baxter International Inc.
- Current Assignee: Baxter International Inc.
- Current Assignee Address: null
- Main IPC: C07C217/28
- IPC: C07C217/28 ; C07C29/04
Abstract:
A two step process for the preparation of polyethylene glycol-bis amine comprising a first step of reacting the terminal hydroxy groups of polyethylene glycol with a halogen substituted aromatic sulfonyl halide in a solvent to form a disubstituted sulfonyl activated polyethylene glycol intermediate. In a second step the intermediate is directly aminated with ammonia to give polyethylene glycol-bis amine.
Information query
