The invention relates to a method of preparing signals (X and Y) to be compared to establish predistortion at the input of an amplifier (12), the signals comprising a signal (X) before amplification and a signal (Y) after amplification by said amplifier. Preparation includes time aligning (22) the signal before amplification (X) with the signal after amplification (Y) before using them to establish said predistortion. The invention preferably operates in two stages, namely a stage of coarse time alignment, in which the signal before amplification (X) is subjected to a time delay comprising an integer number of first time units, and a stage of fine time alignment, in which a delay or advance value of a fraction of the first time unit is determined.