Invention Application
- Patent Title: Taxoid-14-beta-hydroxylases and methods for their use
- Patent Title (中): 紫杉烷-14-β-羟化酶及其使用方法
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Application No.: US10356153Application Date: 2003-01-29
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Publication No.: US20030166176A1Publication Date: 2003-09-04
- Inventor: Rodney B. Croteau , Anne Schoendorf , Stefan Jennewein
- Applicant: Washington State University Research Foundation
- Applicant Address: null
- Assignee: Washington State University Research Foundation
- Current Assignee: Washington State University Research Foundation
- Current Assignee Address: null
- Main IPC: C12P017/02
- IPC: C12P017/02 ; C07H021/04 ; C12N009/02 ; C12P021/02 ; C12N005/04 ; C07D35/14

Abstract:
Oxygenase enzymes and the use of such enzymes to produce paclitaxel (Taxolnull) related taxoids, as well as intermediates in the Taxolnull biosynthetic pathway are disclosed. Also disclosed are nucleic acid sequences encoding the oxygenase enzymes. Particular oxygenase enzymes include the disclosed taxoid-14-beta hydroxylases.
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