发明申请
- 专利标题: ALCAM and ALCAM modulators
- 专利标题(中): ALCAM和ALCAM调制器
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申请号: US10428983申请日: 2003-05-02
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公开(公告)号: US20040048319A1公开(公告)日: 2004-03-11
- 发明人: Jennie P. Mather , Ronghao Li , Mary C. Tsao , Deryk T. Loo
- 主分类号: G01N033/574
- IPC分类号: G01N033/574 ; C07H021/04 ; C07K016/30 ; C12N005/06
摘要:
Provided herein is disclosure about the discovery that the known antigen, ALCAM, is present on a variety of human cancers other than metastasizing malignant melanoma. Also disclosed herein are methods of diagnosing and treating cancers that express ALCAM by using antibodies directed against ALCAM. This invention also discloses compositions and methods for the modulation of ALCAM-mediated neovascularization.
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