发明申请
- 专利标题: Fluorinated di-aryl urea compounds
- 专利标题(中): 氟化二芳基脲化合物
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申请号: US10632998申请日: 2003-08-01
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公开(公告)号: US20040077647A1公开(公告)日: 2004-04-22
- 发明人: Pier Francesco Cirillo , Abdelhakim Hammach , Victor Kamhi , Neil Moss , Paul S. Riska , Christopher Pargellis
- 申请人: Boehringer Ingelheim Pharmaceuticals, Inc.
- 申请人地址: CT Ridgefield
- 专利权人: Boehringer Ingelheim Pharmaceuticals, Inc.
- 当前专利权人: Boehringer Ingelheim Pharmaceuticals, Inc.
- 当前专利权人地址: CT Ridgefield
- 主分类号: A61K031/5377
- IPC分类号: A61K031/5377 ; A61K031/513 ; A61K031/496 ; A61K031/44 ; C07D413/02 ; C07D43/02
摘要:
Disclosed are compounds of formula (I): 1 wherein R1, R2, W and X of formula (I) are defined herein. The compounds inhibit production of cytokines involved in inflammatory processes and are thus useful for treating diseases and pathological conditions involving inflammation such as chronic inflammatory disease. Also disclosed are processes for preparing these compounds and pharmaceutical compositions comprising these compounds.
公开/授权文献
- US06872726B2 Fluorinated di-aryl urea compounds 公开/授权日:2005-03-29
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