发明申请
- 专利标题: Diagnostic agents for pancreatic exocrine function
- 专利标题(中): 胰腺外分泌功能诊断剂
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申请号: US10746327申请日: 2003-12-23
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公开(公告)号: US20040161383A1公开(公告)日: 2004-08-19
- 发明人: Tadashi Kohno , Isaburo Hosoi , Junko Ohshima , Kunihiko Shibata , Asuka Ito
- 申请人: Tokyo Gas Company Limited
- 申请人地址: JP Tokyo
- 专利权人: Tokyo Gas Company Limited
- 当前专利权人: Tokyo Gas Company Limited
- 当前专利权人地址: JP Tokyo
- 优先权: JP324128/1999 19991115
- 主分类号: A61K051/00
- IPC分类号: A61K051/00
摘要:
A diagnostic agent for pancreatic exocrine function comprising an amino acid or a peptide containing at least one 13C or 14C atom, or a pharmaceutically acceptable salt thereof other than Bz-Tyr-13C-PABA is provided. A 13C- or 14C-labeled compound represented by the following formula (II):X2nullR2nullY2nullZ1nullnull(II)or a salt thereof, wherein X2 is a hydrogen atom or a protecting group, R2 is a peptide of 2 to 5 amino acids, an amino acid or a single bond, Y2 is an amino acid, Z1 is an amino acid optionally having a protecting group, and at least one of the amino acids in R2, Y2 and Z1, or at least one of the protecting groups in X2 and Z1 when the protecting groups contain a carbon atom, is 13C or 14C-labeled.
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