发明申请
US20040253695A1 Novel enone reductases, methods for producing same, and methods for selectively reducing a carbon-carbon double bond of an alpha, beta-unsaturated ketone using the reductases
审中-公开
新型烯酮还原酶,其制备方法以及使用还原酶选择性还原α,β-不饱和酮的碳 - 碳双键的方法
- 专利标题: Novel enone reductases, methods for producing same, and methods for selectively reducing a carbon-carbon double bond of an alpha, beta-unsaturated ketone using the reductases
- 专利标题(中): 新型烯酮还原酶,其制备方法以及使用还原酶选择性还原α,β-不饱和酮的碳 - 碳双键的方法
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申请号: US10879250申请日: 2004-06-29
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公开(公告)号: US20040253695A1公开(公告)日: 2004-12-16
- 发明人: Hiroaki Yamamoto , Norihiro Kimoto
- 申请人: Daicel Chemical Industries, Ltd., a Japanese corporation
- 申请人地址: null
- 专利权人: Daicel Chemical Industries, Ltd., a Japanese corporation
- 当前专利权人: Daicel Chemical Industries, Ltd., a Japanese corporation
- 当前专利权人地址: null
- 优先权: JP2001-49363 20010223
- 主分类号: C12P007/26
- IPC分类号: C12P007/26 ; C12N009/04 ; C12N001/21
摘要:
The object of the present invention is to provide novel enone reductases useful for producing ketones. Accordingly, novel enone reductases derived from the genus Kluyveromyces are provided by the present invention. In addition, the present invention also provides genes encoding the enzymes and vectors containing the genes, as well as transformants. Furthermore, the present invention provides enone reductases derived from yeast. Methods for selectively reducing the carbon-carbon double bonds of null,null-unsaturated ketones using these enone reductases are provided. Ketones useful as a raw material for pharmaceuticals can be produced based on an enzymatic reaction.
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