发明申请
- 专利标题： Process for preparing pravastatin sodium
- 专利标题（中）： 制备普伐他汀钠的方法
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申请号： US10490937申请日： 2004-06-01
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公开(公告)号： US20040259216A1公开(公告)日： 2004-12-23
- 发明人: Nam-Hee Choi , Kon-Tae Tak , Ki-Woo Lee , Nam-Hyun Kim , Jong-Chang Jun , Yoon-Jeong Kong , Kyung-Mi Lee
- 优先权： KR2001/60923 20010929
- 主分类号： C12P017/06
- IPC分类号： C12P017/06 ; C12P007/62 ; C12N001/21
摘要：
The present invention relates to a process for preparing pravastatin sodium. More specifically, in the process for preparing pravastatin sodium by adding a precursor of the pravastatin to a microorganism-culturing medium to obtain pravastatin sodium, the precursor of the pravastatin is added to a culture medium that is culturing Streptomyces carbophilus KBT229 (KCCM-10317), which is obtained by UV-mutating a Streptomyces carbophilus FERM BP-1145, and cultured to obtain the pravastatin sodium with high density and high efficiency.
公开/授权文献
- US07223590B2 Process for preparing pravastatin sodium 公开/授权日：2007-05-29
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