发明申请
US20050004080A1 Derivatives of [2-(8,9-dioxo-2,6-diazabicyclo[5.2.0]non-1(7)-en-2-yl)alkyl] phosphonic acid and methods of use thereof
失效
[2-（8,9-二氧代-2,6-二氮杂双环[5.2.0]壬-1（7） - 烯-2-基）烷基]膦酸的衍生物及其使用方法
![Derivatives of [2-(8,9-dioxo-2,6-diazabicyclo[5.2.0]non-1(7)-en-2-yl)alkyl] phosphonic acid and methods of use thereof](/docs/US/2005-01-06/US20050004080A1/abs.jpg.600x600.jpg)
- 专利标题： Derivatives of [2-(8,9-dioxo-2,6-diazabicyclo[5.2.0]non-1(7)-en-2-yl)alkyl] phosphonic acid and methods of use thereof
- 专利标题（中）： [2-（8,9-二氧代-2,6-二氮杂双环[5.2.0]壬-1（7） - 烯-2-基）烷基]膦酸的衍生物及其使用方法
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申请号： US10820216申请日： 2004-04-07
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公开(公告)号： US20050004080A1公开(公告)日： 2005-01-06
- 发明人: Reinhardt Baudy , John Butera
- 申请人： Reinhardt Baudy , John Butera
- 申请人地址： US NJ Madison
- 专利权人： Wyeth
- 当前专利权人： Wyeth
- 当前专利权人地址： US NJ Madison
- 主分类号： A61K31/675
- IPC分类号： A61K31/675 ; C07F9/645
![Derivatives of [2-(8,9-dioxo-2,6-diazabicyclo[5.2.0]non-1(7)-en-2-yl)alkyl] phosphonic acid and methods of use thereof](/abs-image/US/2005/01/06/US20050004080A1/abs.jpg.150x150.jpg)
摘要：
Compounds of formula (I) or pharmaceutically acceptable salts thereof are provided where at least one of R2 or R3 is not hydrogen. The compounds of the present invention are N-methyl-D-aspartate (NMDA) receptor antagonists and are useful in treating a variety of conditions present in a mammal that benefit from inhibiting the NMDA receptor.
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