发明申请
US20050019795A1 Analysis and use of PAR1 polymorphisms for evaluating the risk of cardiovascular disorders
审中-公开
分析和使用PAR1多态性评估心血管疾病风险
- 专利标题: Analysis and use of PAR1 polymorphisms for evaluating the risk of cardiovascular disorders
- 专利标题(中): 分析和使用PAR1多态性评估心血管疾病风险
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申请号: US10831552申请日: 2004-04-23
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公开(公告)号: US20050019795A1公开(公告)日: 2005-01-27
- 发明人: Detlef Kozian , Joerg Czech , Karl-Ernst Siegler , Jean-Francois Deleuze , Sylvain Ricard , Sandrine Mace
- 申请人: Detlef Kozian , Joerg Czech , Karl-Ernst Siegler , Jean-Francois Deleuze , Sylvain Ricard , Sandrine Mace
- 申请人地址: DE Frankfurt
- 专利权人: Aventis Pharma Deutschland GmbH
- 当前专利权人: Aventis Pharma Deutschland GmbH
- 当前专利权人地址: DE Frankfurt
- 优先权: DE10318496.1 20030424
- 主分类号: C07H17/08
- IPC分类号: C07H17/08 ; C07K14/72 ; C12Q1/68 ; C07H21/04
摘要:
The invention relates to polynucleotide sequences comprising genetic variations of the PAR1 gene at positions 3090 and/or 3329. The occurrence of these variants in humans correlates with increased occurrence of particular cardiovascular disorders. The invention furthermore relates to methods for detecting said genetic variations for the purpose of patient diagnosis.
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