Invention Application
- Patent Title: Enzymatically active recombinant glucocerebrosidase
- Patent Title (中): 酶活性重组葡糖脑苷脂酶
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Application No.: US10814025Application Date: 2004-03-31
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Publication No.: US20050019861A1Publication Date: 2005-01-27
- Inventor: James Rasmussen , Gary Barsomian , Michel Bergh
- Applicant: James Rasmussen , Gary Barsomian , Michel Bergh
- Applicant Address: US MA Cambridge
- Assignee: Genzyme Corporation
- Current Assignee: Genzyme Corporation
- Current Assignee Address: US MA Cambridge
- Main IPC: C12N9/24
- IPC: C12N9/24 ; C12N15/85 ; C12N15/866 ; C12P21/02 ; A61K31/445 ; C07H21/04
Abstract:
Recombinant enzymatically active glucocerebrosidase is produced by a eukaryotic cell. Also, a cell includes nucleic acid encoding enzymatically active glucocerebrosidase; also a eukaryotic organism contains such a cell. Also, a method for producing enzymatically active glucocerebrosidase includes steps of introducing glucocerebrosidase-encoding nucleic acid into a eukaryotic cell, causing the cell to express glucocerebrosidase, and purifying the glucocerebrosidase from the cell.
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