Invention Application
- Patent Title: Substituted pyrazole derivatives and related compounds as bradykinin B1 receptor antagonists
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Application No.: US10837231Application Date: 2004-04-30
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Publication No.: US20050020659A1Publication Date: 2005-01-27
- Inventor: Jay Tung , Albert Garofalo , Michael Pleiss , Jing Wu , David Wone , Ashley Guinn , Darren Dressen , R. Neitz , Jennifer Marugg , Martin Neitzel
- Applicant: Jay Tung , Albert Garofalo , Michael Pleiss , Jing Wu , David Wone , Ashley Guinn , Darren Dressen , R. Neitz , Jennifer Marugg , Martin Neitzel
- Main IPC: A61P29/00
- IPC: A61P29/00 ; C07D231/16 ; C07D231/40 ; C07D401/12 ; C07D401/14 ; C07D403/12 ; C07D409/12 ; C07D413/12 ; C07D417/12 ; C07D453/02 ; C07D471/04 ; C07D471/08 ; C07D487/08 ; A61K31/416 ; A61K31/4152
Abstract:
Disclosed are compounds that are bradykinin B1 receptor antagonists and are useful for treating diseases, or relieving adverse symptoms associated with disease conditions, in mammals mediated by bradykinin B1 receptor. Certain of the compounds exhibit increased potency and are also expected to exhibit increased duration of action.
Public/Granted literature
- US07432379B2 Substituted pyrazole derivatives and related compounds as bradykinin B1 receptor antagonists Public/Granted day:2008-10-07
Information query
