Invention Application
US20050026172A1 siRNA libraries optimized for predetermined protein families
审中-公开
针对预定蛋白质家族优化的siRNA文库
- Patent Title: siRNA libraries optimized for predetermined protein families
- Patent Title (中): 针对预定蛋白质家族优化的siRNA文库
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Application No.: US10776399Application Date: 2004-02-10
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Publication No.: US20050026172A1Publication Date: 2005-02-03
- Inventor: Henry Li , Jon Chatterton , Wufang Fan , Ning Ke , Flossie Wong-Staal
- Applicant: Henry Li , Jon Chatterton , Wufang Fan , Ning Ke , Flossie Wong-Staal
- Applicant Address: US CA San Diego 92121
- Assignee: Immusol, Inc.
- Current Assignee: Immusol, Inc.
- Current Assignee Address: US CA San Diego 92121
- Main IPC: C12N15/11
- IPC: C12N15/11 ; C12N15/113 ; C12Q1/68 ; C07H21/02
Abstract:
Libraries for generating small interfering RNA (siRNA) are provided where the members of the library are optimized to inhibit the expression of genes that encode a predetermined family of proteins. The members of the library target at least mRNA encoding all members of the family of proteins. Methods for generating siRNA libraries of the present invention are also provided.
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