发明申请
- 专利标题： Formulation of stabilized cationic transfection agent (s) /nucleic acid particles
- 专利标题（中）： 稳定的阳离子转染剂/核酸颗粒的制剂
-
申请号： US10944872申请日： 2004-09-21
-
公开(公告)号： US20050026287A1公开(公告)日： 2005-02-03
- 发明人: Joel Crouzet , Bruno Pitard
- 申请人： Joel Crouzet , Bruno Pitard
- 专利权人： Aventis Pharma S.A.
- 当前专利权人： Aventis Pharma S.A.
- 优先权： FR97/01,467 19970210
- 主分类号： A61K9/00
- IPC分类号： A61K9/00 ; A61K9/107 ; A61K9/127 ; A61K47/10 ; A61K47/48 ; A61K48/00 ; C12N15/85
摘要：
The invention concerns a composition containing stabilised particles of cationic transfection agent(s)/nucleic acid complexes characterised in that it includes besides said transfection agent and nucleic acid at least a non-ionic surfactant in sufficient amount for preventing the aggregation of the particles in course of time. In a preferred embodiment, the surfactant is a polyoxyalkylene or a derivative thereof.
公开/授权文献
信息查询
