发明申请
US20050034723A1 Substrates for drug delivery device and methods of preparing and use
审中-公开
用于药物输送装置的基材及其制备和使用方法
- 专利标题: Substrates for drug delivery device and methods of preparing and use
- 专利标题(中): 用于药物输送装置的基材及其制备和使用方法
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申请号: US10912417申请日: 2004-08-04
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公开(公告)号: US20050034723A1公开(公告)日: 2005-02-17
- 发明人: Bryson Bennett , Ron Hale , Amy Lu , Daniel Myers , Krishnamohan Sharma , Joshua Rabinowitz
- 申请人: Bryson Bennett , Ron Hale , Amy Lu , Daniel Myers , Krishnamohan Sharma , Joshua Rabinowitz
- 主分类号: A61K9/00
- IPC分类号: A61K9/00 ; A61M11/04 ; A61M11/00 ; A61M15/00
摘要:
An assembly and method for producing a condensation aerosol are disclosed. The assembly includes a heat-conductive metal substrate with an oxidation resistant exterior surface and a drug composition film on the exterior surface and is for use in an aerosol device. The thickness of the film and the surface of the substrate is such that the aerosol formed by vaporizing and condensing the drug composition the aerosol contain 10% by weight or less drug-degradation products and at least 50% of the total amount of the drug composition in the film. The methods for treating the exterior surface include heat and chemical treatment and formation of a protective overcoat.
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