Invention Application
US20050038249A1 Anti-cancer 2,3-dihydro-1H-pyrrole[3,2-f] quinoline compolexes of cobalt and chromium
审中-公开
钴和铬的抗癌2,3-二氢-1H-吡咯并[3,2-f]喹啉类化合物
![Anti-cancer 2,3-dihydro-1H-pyrrole[3,2-f] quinoline compolexes of cobalt and chromium](/docs/US/2005-02-17/US20050038249A1/abs.jpg.600x600.jpg)
- Patent Title: Anti-cancer 2,3-dihydro-1H-pyrrole[3,2-f] quinoline compolexes of cobalt and chromium
- Patent Title (中): 钴和铬的抗癌2,3-二氢-1H-吡咯并[3,2-f]喹啉类化合物
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Application No.: US10928595Application Date: 2004-08-30
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Publication No.: US20050038249A1Publication Date: 2005-02-17
- Inventor: William Denny , William Wilson , David Ware , Graham Atwell , Jared Milbank , Ralph Stevenson
- Applicant: William Denny , William Wilson , David Ware , Graham Atwell , Jared Milbank , Ralph Stevenson
- Applicant Address: NZ Auckland
- Assignee: Auckland Uniservices Limited
- Current Assignee: Auckland Uniservices Limited
- Current Assignee Address: NZ Auckland
- Priority: NZ509540 20010124
- Main IPC: C07D215/30
- IPC: C07D215/30 ; A61K31/404 ; A61K31/437 ; A61K31/47 ; A61P35/00 ; A61P43/00 ; C07D209/60 ; C07D255/02 ; C07D257/00 ; C07D257/02 ; C07D471/04 ; C07F11/00 ; C07F15/06 ; C07F15/00
![Anti-cancer 2,3-dihydro-1H-pyrrole[3,2-f] quinoline compolexes of cobalt and chromium](/abs-image/US/2005/02/17/US20050038249A1/abs.jpg.150x150.jpg)
Abstract:
This invention relates to a class of heterocycles and their metal complexes, and is particularly concerned with the use of these compounds in the preparation of prodrugs or as prodrugs that may be activated under hypoxic conditions by enzymes or by therapeutic ionising radiation, in the treatment of cancer. The invention also relates to the use of these heterocycles and the corresponding metal complexes in the preparation of medicaments and to compositions including the heterocycles or their metal complexes and to methods for preparing these compounds.
Information query
