发明申请
- 专利标题： Molecular target of neurotoxicity
- 专利标题（中）： 神经毒性的分子靶点
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申请号： US10857455申请日： 2004-06-01
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公开(公告)号： US20050043319A1公开(公告)日： 2005-02-24
- 发明人: Fabien Schweighoffer , Philippe Guillet
- 申请人： Fabien Schweighoffer , Philippe Guillet
- 申请人地址： FR Paris
- 专利权人： EXONHIT THERAPEUTICS SA
- 当前专利权人： EXONHIT THERAPEUTICS SA
- 当前专利权人地址： FR Paris
- 优先权： FR01/10819 20010814
- 主分类号： A61K31/00
- IPC分类号： A61K31/00 ; C12Q1/44 ; C12Q1/68 ; A61K31/519 ; A61K31/522
摘要：
The present invention relates to the fields of biology, genetics and medicine. In particular it concerns new methods for the detection, characterisation and/or treatment (or management) of neurodegenerative diseases, particularly amyotrophic lateral sclerosis. The invention equally concerns methods for identifying or screening compounds active in these diseases. The invention further concerns the compounds, genes, cells, plasmids or compositions useful for implementing the hereinabove methods. In particular, the invention describes the role of PDE4B in these diseases and its use as a therapeutic, diagnostic or experimental target.
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