- 专利标题： Quinazoline derivatives as antitumor agents
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申请号： US10494137申请日： 2002-10-31
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公开(公告)号： US20050043336A1公开(公告)日： 2005-02-24
- 发明人: Laurent Hennequin , Jason Kettle , Martin Pass , Robert Bradbury
- 申请人： Laurent Hennequin , Jason Kettle , Martin Pass , Robert Bradbury
- 优先权： GB0126433.2 20011103; GB0129059.2 20011205
- 国际申请： PCT/GB02/04931 WO 20021031
- 主分类号： A61K31/517
- IPC分类号： A61K31/517 ; A61K31/5377 ; A61K31/55 ; A61P9/08 ; A61P9/10 ; A61P13/08 ; A61P13/10 ; A61P17/06 ; A61P35/00 ; A61P35/02 ; A61P43/00 ; C07D239/94 ; C07D401/12 ; C07D401/14 ; C07D403/12 ; C07D405/12 ; C07D405/14 ; C07D409/12 ; C07D409/14 ; C07D411/12 ; C07D413/12 ; C07D413/14 ; C07D417/14 ; C07D471/04
摘要：
The invention concerns quinazoline derivatives of Formula (I); wherein each of Q1, Q2, Z, R1, R2, R3, and m have any of the meanings defined in the description; processes for their preparation, pharmaceutical compositions containing them and their use in the manufacture of a medicament for use in the prevention or treatment of tumours which are sensitive to inhibition of erbB receptor tyrosin kinases.
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