- 专利标题： Monoclonal antibodies to human immunodeficiency virus and uses thereof
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申请号： US10940344申请日： 2004-09-14
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公开(公告)号： US20050053925A1公开(公告)日： 2005-03-10
- 发明人: Sheng Lou , Jeffrey Hunt , John Konrath , Xiaoxing Qiu , James Scheffel , Joan Tyner
- 申请人： Sheng Lou , Jeffrey Hunt , John Konrath , Xiaoxing Qiu , James Scheffel , Joan Tyner
- 主分类号： G01N33/569
- IPC分类号： G01N33/569 ; C07K14/16 ; C07K16/10 ; C12N5/10 ; C12N5/20 ; C12N15/02 ; C12P21/08 ; C12Q1/70 ; C12N5/06
摘要：
The present invention relates to novel monoclonal antibodies which may be used in the detection of Human Immunodeficiency Virus (HIV). These antibodies exhibit an unusually high degree of sensitivity, a remarkably broad range of specificity, and bind to novel shared, non-cross-reactive epitopes. In particular, the monoclonal antibodies of the present invention may be utilized to detect HIV-1 antigen and HIV-2 core antigen in a patient sample.
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