Invention Application
US20050059028A1 RNAi-based sensors, caged interfering RNAs, and methods of use thereof
审中-公开
基于RNAi的传感器，笼式干扰RNA及其使用方法
- Patent Title: RNAi-based sensors, caged interfering RNAs, and methods of use thereof
- Patent Title (中): 基于RNAi的传感器，笼式干扰RNA及其使用方法
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Application No.: US10716393Application Date: 2003-11-17
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Publication No.: US20050059028A1Publication Date: 2005-03-17
- Inventor: Quan Nguyen , Gary McMaster
- Applicant: Quan Nguyen , Gary McMaster
- Assignee: GenoSpectra, Inc.
- Current Assignee: GenoSpectra, Inc.
- Main IPC: A61K48/00
- IPC: A61K48/00 ; C07H21/02 ; C12N15/85 ; C12Q1/00 ; C12Q1/37 ; C12Q1/48 ; C12Q1/68 ; G01N33/542 ; G01N33/573
Abstract:
Methods of using labeled interfering RNAs to detect and/or quantitate target mRNAs in cells are provided. Related compositions, systems, and kits are also provided. Caged interfering RNAs (e.g., photoactivatable interfering RNAs), methods of using such caged RNAs, and related systems and kits are also provided. Methods and compositions for introducing interfering RNAs into cells, using RNAs covalently associated with protein transduction domains and/or lipids, are provided. Also provided are methods and compositions for selectively attenuating expression of a target mRNA by controlling expression of an interfering RNA.
Information query
