发明申请
- 专利标题： Rabconnectin-3-binding protein
- 专利标题（中）： Rabconnectin-3结合蛋白
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申请号： US10645335申请日： 2003-08-21
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公开(公告)号： US20050064430A1公开(公告)日： 2005-03-24
- 发明人: Masakazu Takeuchi , Yoshimi Takai
- 申请人： Masakazu Takeuchi , Yoshimi Takai
- 优先权： JP2002-319521 20021101
- 主分类号： C07K14/47
- IPC分类号： C07K14/47 ; C12Q1/68 ; C07H21/04 ; C07K14/705 ; C12N9/10
摘要：
A protein useful for clarifying the regulation mechanism of Ca2+-dependent exocytosis in particular, the activation and inactivation of Rab3A, and a method of screening for a material useful for regulating Ca2+-dependent exocytosis in particular, the activation and inactivation of Rab3A, using the above protein. By using the coimmunoprecipitation with an anti-Rab3A GEP antibody, a protein participated in the regulation of activation or inactivation of Rab3A is determined. As the protein binds to rabconnectin-3 and GDP/GTP exchange protein, it can be used for screening for a material that increases or decreases the binding.
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