发明申请
- 专利标题： Method of expressing foreign gene in kidney
- 专利标题（中）： 在肾脏中表达外源基因的方法
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申请号： US10478537申请日： 2002-05-24
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公开(公告)号： US20050070014A1公开(公告)日： 2005-03-31
- 发明人: Hiroki Maruyama , Jun-ichi Miyazaki
- 申请人： Hiroki Maruyama , Jun-ichi Miyazaki
- 优先权： JP2001-157810 20010525; JP2002-032230 20020208
- 国际申请： PCT/JP02/05067 WO 20020524
- 主分类号： C12N15/09
- IPC分类号： C12N15/09 ; A61K31/711 ; A61K48/00 ; A61P13/12 ; C07K14/47 ; C07K14/505 ; C12N5/10 ; C12N15/85
摘要：
The invention of this application provides a method of expressing a gene, which comprises transferring a plasmid vector recombined with an exogenous gene into the kidney by administration via the renal vein so that the exogenous gene is expressed mainly in renal interstitial fibroblasts. The method of this invention can transfer the exogenous gene into the kidneys safely and efficiently and express the transgene over a long period of time.
公开/授权文献
- US07381709B2 Method of expressing foreign gene in kidney 公开/授权日：2008-06-03
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