发明申请
US20050075325A1 Selective D1/D5 receptor antagonists for the treatment of obesity and CNS disorders
失效
选择性D1 / D5受体拮抗剂用于治疗肥胖和CNS疾病
- 专利标题： Selective D1/D5 receptor antagonists for the treatment of obesity and CNS disorders
- 专利标题（中）： 选择性D1 / D5受体拮抗剂用于治疗肥胖和CNS疾病
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申请号： US10850530申请日： 2004-05-20
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公开(公告)号： US20050075325A1公开(公告)日： 2005-04-07
- 发明人: Duane Burnett , William Greenlee , Brian McKirtrick , Jing Su , Zhaoning Zhu , Thavalakulamgara Sasikumar , Robert Mazzola , Li Qiang , Yuanzan Ye
- 申请人： Duane Burnett , William Greenlee , Brian McKirtrick , Jing Su , Zhaoning Zhu , Thavalakulamgara Sasikumar , Robert Mazzola , Li Qiang , Yuanzan Ye
- 专利权人： Schering Corporation
- 当前专利权人： Schering Corporation
- 主分类号： C07D223/14
- IPC分类号： C07D223/14 ; C07D401/12 ; C07D403/10 ; C07D407/12 ; A61K31/55 ; C07D43/02
摘要：
The present invention provides compounds, which, are novel antagonists for D1/D5 receptors as well as methods for preparing such compounds. In another embodiment, the invention provides pharmaceutical compositions comprising such D1/D5 receptor antagonists as well as methods of using them to treat CNS disorders, obesity, metabolic disorders, eating disorders such as hyperphagia, and diabetes.
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