- 专利标题： Compositions and methods for topical delivery of oligonucleotides
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申请号： US10876962申请日： 2004-06-25
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公开(公告)号： US20050096287A1公开(公告)日： 2005-05-05
- 发明人: Rahul Mehta , Gregory Hardee , Phillip Cook , David Ecker , Yali Tsai , Michael Templin
- 申请人： Rahul Mehta , Gregory Hardee , Phillip Cook , David Ecker , Yali Tsai , Michael Templin
- 主分类号： C12N15/09
- IPC分类号： C12N15/09 ; A61K9/107 ; A61K31/7088 ; A61K31/7125 ; A61K47/12 ; A61K47/24 ; A61K47/38 ; A61K48/00 ; C07H21/04 ; C12Q1/68
摘要：
The present invention relates to compositions and methods which enhance the delivery of oligonucleotides and other nucleosidic moieties via topical routes of administration. Preferred compositions include liposomes or penetration enhancers for the delivery of such moieties to dermal and/or epidermal tissue in an animal for investigative, therapeutic or prophylactic purposes.
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