发明申请
- 专利标题： Notch1 inhibitors for inducing apoptosis
- 专利标题（中）： Notch1诱导凋亡抑制剂
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申请号： US10991147申请日： 2004-11-17
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公开(公告)号： US20050096292A1公开(公告)日： 2005-05-05
- 发明人: Susan Freier , Kenneth Dobie , Erich Koller
- 申请人： Susan Freier , Kenneth Dobie , Erich Koller
- 主分类号： A61K38/00
- IPC分类号： A61K38/00 ; C12N15/113 ; C07H21/04 ; A61K48/00
摘要：
Compounds, compositions and methods are provided for modulating the expression of Notch1. The compositions comprise oligonucleotides, targeted to nucleic acid encoding Notch1. Methods of using these compounds for modulation of Notch1 expression and for diagnosis and treatment of disease associated with expression Notch1 are provided.
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