发明申请
US20050096312A1 Therapeutic quinolone compounds with 5-ht-antagonistic properties 审中-公开
具有5-ht拮抗作用的治疗性喹诺酮化合物

Therapeutic quinolone compounds with 5-ht-antagonistic properties
摘要:
Provided herein is a compound having the formula (I), (R2 is typically a tertiary nitrogen atom, being either alkyl-substituted or member of a heterocyclic ring; R7 is typically a monocyclic or bicyclic aromatic ring or a heterocyclic ring) wherein said compounds are useful for the treatment of psychiatric disorders including but not limited to depression, generalized anxiety, eating disorders, dementia, panic disorder, and sleep disorders. The compounds may also be useful in the treatment of gastrointestinal disorders, cardiovascular regulation, motor disorders, endocrine disorders, vasospasm and sexual dysfunction. The compounds are 5HT1B and 5HT1D antagonists.
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