发明申请
US20050096360A1 Inhibitors of semicarbazide-sensitive amine oxidase (SSAO) and VAP-1 mediated adhesion useful for treatment of diseases
审中-公开
氨基脲敏感性胺氧化酶（SSAO）和VAP-1介导的粘附抑制剂可用于治疗疾病
- 专利标题： Inhibitors of semicarbazide-sensitive amine oxidase (SSAO) and VAP-1 mediated adhesion useful for treatment of diseases
- 专利标题（中）： 氨基脲敏感性胺氧化酶（SSAO）和VAP-1介导的粘附抑制剂可用于治疗疾病
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申请号： US10913253申请日： 2004-08-06
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公开(公告)号： US20050096360A1公开(公告)日： 2005-05-05
- 发明人: Luisa Salter-Cid , Eric Wang , Keith Cockerill , Matthew Linnik , Edward Victoria
- 申请人： Luisa Salter-Cid , Eric Wang , Keith Cockerill , Matthew Linnik , Edward Victoria
- 主分类号： C07C211/26
- IPC分类号： C07C211/26 ; C07C211/27 ; C07C239/20 ; C07C243/18 ; A61K31/44 ; A61K31/15
摘要：
Compositions and methods of using compositions for treatment of inflammatory diseases and immune disorders are provided. Allylhydrazine compounds, hydroxylamine (aminooxy) compounds, and other compounds are disclosed which are inhibitors of semicarbazide-sensitive amine oxidase (SSAO) and/or vascular adhesion protein 1 (VAP-1). The compounds have therapeutic utility in suppressing inflammation and inflammatory responses, and in treatment of several disorders, including multiple sclerosis.
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