发明申请
- 专利标题: Fabrication of drug loaded biodegradable polymer fibers
- 专利标题(中): 装载药物的可生物降解聚合物纤维的制造
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申请号: US11019801申请日: 2004-12-21
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公开(公告)号: US20050106211A1公开(公告)日: 2005-05-19
- 发明人: Kevin Nelson , Andres Romero-Sanchez , George Smith , Nadir Alikacem , Delia Radulescu , Paula Waggoner , Zhibing Hu
- 申请人: Kevin Nelson , Andres Romero-Sanchez , George Smith , Nadir Alikacem , Delia Radulescu , Paula Waggoner , Zhibing Hu
- 主分类号: A61K9/00
- IPC分类号: A61K9/00 ; A61K9/70 ; A61K31/7088 ; A61K38/00 ; A61K47/34 ; A61K47/36 ; A61L27/00 ; A61L27/54 ; A61L27/58 ; A61P7/00 ; A61P35/00 ; A61P37/02 ; D01F1/10 ; D01F6/62 ; D01F8/14 ; D06M15/03 ; D06M16/00 ; A61F2/00
摘要:
The invention provides tissue engineering compositions and methods wherein three-dimensional matrices for growing cells are prepared for in vitro and in vivo use. The matrices comprise biodegradable polymer fibers capable of the controlled delivery of therapeutic agents. The spatial and temporal distribution of released therapeutic agents is controlled by use of defined nonhomogeneous patterns of therapeutic agents in the matrices.
公开/授权文献
- US07514095B2 Fabrication of drug loaded biodegradable polymer fibers 公开/授权日:2009-04-07