发明申请
US20050107471A1 NEW ESTERS OF 5-AMINOLEVULINIC ACID AND THEIR USE AS PHOTOSENSITIZING COMPOUNDS IN PHOTOCHEMOTHERAPY
有权
5-氨基酸的新产物及其在光电疗法中的光敏化合物的使用
- 专利标题: NEW ESTERS OF 5-AMINOLEVULINIC ACID AND THEIR USE AS PHOTOSENSITIZING COMPOUNDS IN PHOTOCHEMOTHERAPY
- 专利标题(中): 5-氨基酸的新产物及其在光电疗法中的光敏化合物的使用
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申请号: US10966408申请日: 2004-10-14
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公开(公告)号: US20050107471A1公开(公告)日: 2005-05-19
- 发明人: Karl Gierskcky , Johan Moan , Qian Peng , Harald Steen , Trond Warloe , Alf Bjorseth , Jo Klaveness , Nils Nilsen , Jon Braenden , Aslak Godal
- 申请人: Karl Gierskcky , Johan Moan , Qian Peng , Harald Steen , Trond Warloe , Alf Bjorseth , Jo Klaveness , Nils Nilsen , Jon Braenden , Aslak Godal
- 优先权: GB9504948.2 19950310; GB9525822.4 19951218
- 主分类号: A61K41/00
- IPC分类号: A61K41/00 ; A61K49/00 ; C07C229/22 ; A61K31/22
摘要:
The present invention relates to compounds being esters of 5-aminolevulinic acids or pharmaceutically acceptable salts thereof, including compounds of formula (I) R22N—CH2COCH2—CH2CO—OR1 (wherein R1 may represent alkyl optionally substituted by hydroxy, alkoxy, acyloxy, alkoxycarbonyloxy, amino, aryl, oxo or fluoro groups and optionally interrupted by oxygen, nitrogen, sulphur or phosphorus atoms; and R2 represents a hydrogen atom or a group R1, and both R2 groups may be the identical or different), and their use in diagnosis and photochemotherapy of disorders or abnormalities of external or internal surfaces of the body, and products and kits for performing the invention.
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