发明申请
US20050112702A1 Methods of identifying compounds that modulate IL-4 receptor mediated IgE synthesis utilizing a CLLD8 protein
有权
鉴定使用CLLD8蛋白调节IL-4受体介导的IgE合成的化合物的方法
- 专利标题: Methods of identifying compounds that modulate IL-4 receptor mediated IgE synthesis utilizing a CLLD8 protein
- 专利标题(中): 鉴定使用CLLD8蛋白调节IL-4受体介导的IgE合成的化合物的方法
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申请号: US11027949申请日: 2004-12-30
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公开(公告)号: US20050112702A1公开(公告)日: 2005-05-26
- 发明人: Esteban Masuda , Todd Kinsella , Justin Warner , Taisei Kinoshita , Mark Bennett , David Anderson
- 申请人: Esteban Masuda , Todd Kinsella , Justin Warner , Taisei Kinoshita , Mark Bennett , David Anderson
- 申请人地址: US CA South San Francisco
- 专利权人: Rigel Pharmaceuticals, Inc.
- 当前专利权人: Rigel Pharmaceuticals, Inc.
- 当前专利权人地址: US CA South San Francisco
- 主分类号: A61K38/17
- IPC分类号: A61K38/17 ; C07K7/08 ; C07K14/54 ; G01N33/68 ; G01N33/53 ; G01N33/567
摘要:
The present provides compounds capable of modulating IL-4 receptor-mediated IgE production, as well as IL-4 induced processes associated therewith, methods and kits for identifying such compounds that utilize a CLLD8 protein as a surrogate analyte and methods of using the compounds in a variety of in vitro, in vitro and ex vivo contexts.
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