发明申请
US20050113458A1 Use of 1-aminocyclohexane derivatives to modify deposition of fibrillogenic a-beta peptides in amyloidopathies
审中-公开
使用1-氨基环己烷衍生物改变淀粉样蛋白病中纤维蛋白原α-β肽的沉积
- 专利标题： Use of 1-aminocyclohexane derivatives to modify deposition of fibrillogenic a-beta peptides in amyloidopathies
- 专利标题（中）： 使用1-氨基环己烷衍生物改变淀粉样蛋白病中纤维蛋白原α-β肽的沉积
-
申请号： US10971306申请日： 2004-10-22
-
公开(公告)号： US20050113458A1公开(公告)日： 2005-05-26
- 发明人: Sandeep Gupta , Pradeep Banerjee , Debomoy Lahiri , Martin Farlow
- 申请人： Sandeep Gupta , Pradeep Banerjee , Debomoy Lahiri , Martin Farlow
- 申请人地址： US NY New York
- 专利权人： Forest Laboratories, Inc.
- 当前专利权人： Forest Laboratories, Inc.
- 当前专利权人地址： US NY New York
- 主分类号： A61K31/13
- IPC分类号： A61K31/13
摘要：
The invention relates to the use of NMDA receptor antagonists such as 1-aminocyclohexane derivatives to modify deposition of potentially toxic and fibrillogenic Aβ peptides in amyloidopathies. Specifically, the invention relates to the ability of memantine to intervene in the processing of APP and decrease the levels of fibrillogenic Aβ peptides.
信息查询
