发明申请
US20050119292A1 3-Cyclyl-5-(nitrogen-containing 5-membered ring)methyl-oxazolidinone derivatives and their use as antibacterial agents
失效
3-环-5-（含氮5元环）甲基 - 恶唑烷酮衍生物及其作为抗菌剂的用途
- 专利标题： 3-Cyclyl-5-(nitrogen-containing 5-membered ring)methyl-oxazolidinone derivatives and their use as antibacterial agents
- 专利标题（中）： 3-环-5-（含氮5元环）甲基 - 恶唑烷酮衍生物及其作为抗菌剂的用途
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申请号： US10506020申请日： 2003-02-25
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公开(公告)号： US20050119292A1公开(公告)日： 2005-06-02
- 发明人: Michael Gravestock , Neil Hales , Folkert Reck , Fei Zhou , Paul Fleming , Daniel Carcanague , Marc Girardot
- 申请人： Michael Gravestock , Neil Hales , Folkert Reck , Fei Zhou , Paul Fleming , Daniel Carcanague , Marc Girardot
- 国际申请： PCT/GB03/00785 WO 20030225
- 主分类号： C07D413/14
- IPC分类号： C07D413/14 ; A61K31/422 ; A61K31/454 ; A61K31/541 ; A61P31/04 ; C07D413/06 ; C07D413/10 ; C07D417/14 ; C07D521/00 ; A61K31/4439 ; A61K31/4747
摘要：
Compounds of the formula (I), or a pharmaceutically-acceptable salt, or an in-vivo-hydrolysable ester thereof, wherein —N-HET is, for example, (Ic) or (If) wherein R1 is (1-4C)alkyl; Q is selected from, for example, Q1 wherein R2 and R3 are independently hydrogen or fluoro; T is selected from a range of groups, for example, wherein m is 0, 1 or 2; are useful as antibacterial agents; and processes for their manufacture and pharmaceutical compositions containing them are described.
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