发明申请
- 专利标题： Peptidically buffered formulations for electrotransport applications and methods of making
- 专利标题（中）： 用于电转运应用的肽缓冲制剂和制备方法
-
申请号： US10993649申请日： 2004-11-19
-
公开(公告)号： US20050142531A1公开(公告)日： 2005-06-30
- 发明人: David Rauser , Rama Padmanabhan , Joseph Phipps , Michel Cormier
- 申请人： David Rauser , Rama Padmanabhan , Joseph Phipps , Michel Cormier
- 主分类号： A01N1/00
- IPC分类号： A01N1/00 ; A61K9/00 ; A61K31/74 ; A61N1/30
摘要：
Methods for preparing compositions for use in electrotransport delivery systems. The method includes providing a drug solution comprising drug ions and associated counterions; adjusting the pH of the drug solution by contacting the drug solution with a ion exchange material first; separating the ion exchange material from the pH-adjusted drug solution; and buffering the pH-adjusted drug solution with a buffer. A peptidic buffer is preferably used. The methods result in compositions suitable for use in electrotransport delivery systems.
信息查询
