发明申请
- 专利标题： Biomarkers for amyotrophic lateral sclerosis
- 专利标题（中）： 用于肌萎缩性侧索硬化症的生物标记物
-
申请号： US10972732申请日： 2004-10-25
-
公开(公告)号： US20050148026A1公开(公告)日： 2005-07-07
- 发明人: Robert Bowser , Srikanth Ranganathan
- 申请人： Robert Bowser , Srikanth Ranganathan
- 申请人地址： US PA Pittsburgh
- 专利权人： University of Pittsburgh of the Commonwealth System of Higher Education
- 当前专利权人： University of Pittsburgh of the Commonwealth System of Higher Education
- 当前专利权人地址： US PA Pittsburgh
- 主分类号： C12Q
- IPC分类号： C12Q20060101 ; G01N33/00 ; G01N33/53 ; G01N33/68
摘要：
The invention provides a method for diagnosing amyotrophic lateral sclerosis (ALS) in a subject, a method for assessing the effectiveness of a drug in treating ALS, and a method for determining the site of onset of ALS in a subject. Each method comprises (a) obtaining a sample from the subject, (b) analyzing the proteins in the sample by mass spectroscopy, and (c) determining a mass spectral profile for the sample. In some embodiments, the method comprises comparing the mass spectral profile of the sample to the mass spectral profile of a positive or a negative standard.
公开/授权文献
- US07858071B2 Biomarkers for amyotrophic lateral sclerosis 公开/授权日：2010-12-28
信息查询
