Invention Application
US20050158296A1 Use of p97 as an enzyme delivery system for the delivery of therapeutic lysosomal enzymes
审中-公开
使用p97作为递送治疗性溶酶体酶的酶递送系统
- Patent Title: Use of p97 as an enzyme delivery system for the delivery of therapeutic lysosomal enzymes
- Patent Title (中): 使用p97作为递送治疗性溶酶体酶的酶递送系统
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Application No.: US10501028Application Date: 2003-01-10
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Publication No.: US20050158296A1Publication Date: 2005-07-21
- Inventor: Christopher Starr , Todd Zankel
- Applicant: Christopher Starr , Todd Zankel
- International Application: PCT/US03/00894 WO 20030110
- Main IPC: A61K38/17
- IPC: A61K38/17 ; A61K38/44 ; A61K47/48 ; C12P21/04 ; G01N33/50 ; G01N33/566

Abstract:
The present invention provides for compositions and methods for treating, ameliorating or preventing a lysosomal storage disease by administering to a patient suffering from a lysosomal storage disease a P97 conjugated with an enzyme which is capable of transportation into the lysosomes of cells on either sides of the blood brain barrier.
Information query
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