发明申请
- 专利标题: Inhibitors of akt activity
- 专利标题(中): akt活性抑制剂
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申请号: US10510066申请日: 2003-04-04
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公开(公告)号: US20050159422A1公开(公告)日: 2005-07-21
- 发明人: Craig Lindsley , Zhijian Zhao
- 申请人: Craig Lindsley , Zhijian Zhao
- 国际申请: PCT/US03/10447 WO 20030404
- 主分类号: A61K31/498
- IPC分类号: A61K31/498 ; A61K31/4985 ; A61K45/00 ; A61P35/00 ; A61P43/00 ; C07D241/36 ; C07D401/14 ; C07D487/02 ; C07D487/04 ; C07D519/00 ; C07D519/04
摘要:
The present invention is directed to compounds comprising a ring-fused quinoxalinyl moiety which inhibit the activity of Akt, a serine/threonine protein kinase. The invention is further directed to chemotherapeutic compositions containing the compounds of this invention and methods for treating cancer comprising administration of the compounds of the invention.
公开/授权文献
- US07273869B2 Inhibitors of Akt activity 公开/授权日:2007-09-25
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