发明申请
- 专利标题： Quinazoline derivatives
- 专利标题（中）： 喹唑啉衍生物
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申请号： US10857342申请日： 2004-06-01
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公开(公告)号： US20050165035A1公开(公告)日： 2005-07-28
- 发明人: Robert Bradbury , Jason Kettle , James McCabe , Andrew Turner , Laurent Hennequin
- 申请人： Robert Bradbury , Jason Kettle , James McCabe , Andrew Turner , Laurent Hennequin
- 专利权人： AstraZeneca AB
- 当前专利权人： AstraZeneca AB
- 优先权： GB0317665.8 20030729
- 主分类号： C07D401/12
- IPC分类号： C07D401/12 ; A61K31/517 ; C07D43/02
摘要：
The invention concerns quinazoline derivatives of Formula I wherein R1 and R2 have any of the meanings defined in the description; processes for their preparation, pharmaceutical compositions containing them and their use in the manufacture of a medicament for use as an antiproliferative agent in the prevention or treatment of tumours which are sensitive to inhibition of erbB, particularly EGF, receptor tyrosine kinases.
公开/授权文献
- US07148230B2 Quinazoline derivatives 公开/授权日：2006-12-12