Invention Application
- Patent Title: Nf-kb inhibitors
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Application No.: US10510841Application Date: 2003-04-11
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Publication No.: US20050165086A1Publication Date: 2005-07-28
- Inventor: James Callahan , Yue Li
- Applicant: James Callahan , Yue Li
- International Application: PCT/US03/11297 WO 20030411
- Main IPC: C07D333/50
- IPC: C07D333/50 ; A61K31/381 ; A61P1/00 ; A61P3/10 ; A61P9/00 ; A61P9/08 ; A61P9/10 ; A61P11/00 ; A61P11/06 ; A61P13/12 ; A61P17/00 ; A61P17/06 ; A61P19/04 ; A61P19/10 ; A61P25/00 ; A61P25/28 ; A61P29/00 ; A61P31/12 ; A61P31/18 ; A61P35/00 ; A61P37/02 ; A61P43/00 ; C07D333/74 ; C07D333/78 ; C07D333/76
Abstract:
The present invention provides novel compounds and methods for using them to treat diseases with aminothiophene inhibitors of IKK-β phosphorylation of IκB. In so doing these aminothiophene inhibitors block pathological activation of transcription factor NF-κB in which diseases excessive activation of NF-κB is implicated.
Public/Granted literature
- US07183311B2 NF-κB inhibitors Public/Granted day:2007-02-27
Information query
