发明申请
- 专利标题: Crystalline base of citalopram
- 专利标题(中): 西酞普兰的结晶基
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申请号: US11090336申请日: 2005-03-24
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公开(公告)号: US20050165092A1公开(公告)日: 2005-07-28
- 发明人: Hans Petersen , Klaus Bogeso , Per Holm
- 申请人: Hans Petersen , Klaus Bogeso , Per Holm
- 申请人地址: DK Valby-Copenhagen
- 专利权人: H. Lundbeck A/S
- 当前专利权人: H. Lundbeck A/S
- 当前专利权人地址: DK Valby-Copenhagen
- 优先权: WOPCT/DK00/00183 20000413; DKPA200000402 20000313
- 主分类号: C07D307/87
- IPC分类号: C07D307/87 ; A61J3/10 ; A61K9/20 ; A61K31/00 ; A61K31/34 ; A61K31/343 ; A61P25/00 ; A61P25/24 ; C07C209/86 ; C07C253/14 ; C07D20060101 ; C07D307/84
摘要:
The present invention relates to the crystalline base of the well known antidepressant drug citalopram, 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-5-isobenzofurancarbonitrile, formulations of said base, a process for the preparation of purified salts of citalopram, such as the hydrobromide, using the base, the salts obtained by said process and formulations containing such salts.
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