发明申请
US20050175615A1 Therapeutic vaccine targeted against P-glycoprotein 170 for inhibiting multidrug resistance in the treatment of cancers
有权
针对P-糖蛋白170的治疗性疫苗用于抑制癌症治疗中的多药耐药性
- 专利标题： Therapeutic vaccine targeted against P-glycoprotein 170 for inhibiting multidrug resistance in the treatment of cancers
- 专利标题（中）： 针对P-糖蛋白170的治疗性疫苗用于抑制癌症治疗中的多药耐药性
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申请号： US10902276申请日： 2004-07-30
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公开(公告)号： US20050175615A1公开(公告)日： 2005-08-11
- 发明人: Pierre-Francois Tosi , Claudine Madoulet , Claude Nicolau , David Hickman
- 申请人： Pierre-Francois Tosi , Claudine Madoulet , Claude Nicolau , David Hickman
- 优先权： FRFR0309188 20030725
- 主分类号： A61K39/00
- IPC分类号： A61K39/00 ; A61K39/395
摘要：
The invention relates to an immunogenic composition which comprises, firstly, a carrier and, secondly, as antigenic structure, conjugates comprising all or part of the amino acid sequences of at least one peptide derived from an extracellular loop of the P-170 protein, each peptide being combined with several molecules of fatty acid containing a carbon chain of between C12 and C24 so as to allow, under suitable administration conditions, the induction of anti-P-170 antibodies. The invention relates to said composition for defining means for treating multidrug resistances.
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