发明申请
US20050175989A1 Method and detector for identifying subtypes of human papilloma viruses
审中-公开
用于鉴定人乳头状瘤病毒亚型的方法和检测器
- 专利标题: Method and detector for identifying subtypes of human papilloma viruses
- 专利标题(中): 用于鉴定人乳头状瘤病毒亚型的方法和检测器
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申请号: US10601497申请日: 2003-06-23
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公开(公告)号: US20050175989A1公开(公告)日: 2005-08-11
- 发明人: Ching-Yu Lin , Ruey-Wen Lin , Chiou-Mien You , Chiu-Cho Yan , Bor-Heng Lee , Hsien-Hsiung Lee , Yu-Ju Lin , Chih-Chun Fan , Han-Chuan Hsu , Chia-Wen Shih , Chih-Hsing Yeh , Yi-Feng Kao , Chih-Long Pan , Yen-Ming Lin , Peter Chan
- 申请人: Ching-Yu Lin , Ruey-Wen Lin , Chiou-Mien You , Chiu-Cho Yan , Bor-Heng Lee , Hsien-Hsiung Lee , Yu-Ju Lin , Chih-Chun Fan , Han-Chuan Hsu , Chia-Wen Shih , Chih-Hsing Yeh , Yi-Feng Kao , Chih-Long Pan , Yen-Ming Lin , Peter Chan
- 主分类号: C12Q1/68
- IPC分类号: C12Q1/68 ; C12Q1/70
摘要:
A detector for detecting and simultaneously diagnosing at least one subtype of human papilloma viruses (HPV) contained in a biological sample is provided. The detector comprises: a carrier, a plurality of micro-dots immobilized on the carrier, wherein each micro-dot is for identifying one particular HPV subtype, and the HPV subtype is one selected from a group consisting of 39 different HPV subtypes; and at least one oligonucleotide sequence contained in each the micro-dot that is specific to the one particular HPV subtype, wherein the at least one oligonucleotide sequence serves as a detection probe that hybridizes specifically with an L1 gene sequence of the one particular HPV subtype to form a hybridization complex as a detection indicator, so that each micro-dot identifies one particular HPV subtype via a corresponding oligonucleotide of the one particular HPV subtype, and thereby detecting and simultaneously identifying subtypes of human papilloma viruses.
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