发明申请
US20050186567A1 Antisense modulation of peroxisome proliferator-activated receptor gamma expression
审中-公开
过氧化物酶体增殖物激活受体γ表达的反义调节
- 专利标题： Antisense modulation of peroxisome proliferator-activated receptor gamma expression
- 专利标题（中）： 过氧化物酶体增殖物激活受体γ表达的反义调节
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申请号： US10181176申请日： 2001-01-11
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公开(公告)号： US20050186567A1公开(公告)日： 2005-08-25
- 发明人: Robert McKay , Alexander Borchers , Brenda Baker
- 申请人： Robert McKay , Alexander Borchers , Brenda Baker
- 优先权： US09/484,345 20000118
- 国际申请： PCT/US01/00952 WO 20010111
- 主分类号： C12N15/09
- IPC分类号： C12N15/09 ; A61K31/7115 ; A61K31/712 ; A61K31/7125 ; A61K38/00 ; A61K45/00 ; A61K48/00 ; A61P1/00 ; A61P3/10 ; A61P9/00 ; A61P29/00 ; A61P35/00 ; A61P43/00 ; C12N15/113 ; C12Q1/68 ; C07H21/02
摘要：
Antisense compounds, compositions and methods are provided for modulating the expression of Peroxisome proliferator-activated receptor gamma. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding Peroxisome proliferator-activated receptor gamma Methods of using these compounds for modulation of Peroxisome proliferator-activated receptor gamma expression and for treatment of diseases associated with expression of Peroxisome proliferator-activated receptor gamma are provided.
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