发明申请
- 专利标题： Substituted benzimidazole compounds
- 专利标题（中）： 取代的苯并咪唑化合物
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申请号： US10632888申请日： 2003-08-01
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公开(公告)号： US20050203158A1公开(公告)日： 2005-09-15
- 发明人: Joerg Bentzien , Brian Cook , Charles Cywin , Roman Fleck , Ho Lo , Peter Nemoto , Steven Pullen , Gregory Roth , Roger Snow , Hidenori Takahashi , Ji Wang , Kevin Moriarty , Lei Qiao , Michael Winters
- 申请人： Joerg Bentzien , Brian Cook , Charles Cywin , Roman Fleck , Ho Lo , Peter Nemoto , Steven Pullen , Gregory Roth , Roger Snow , Hidenori Takahashi , Ji Wang , Kevin Moriarty , Lei Qiao , Michael Winters
- 申请人地址： US CT Ridgefield
- 专利权人： Boehringer Ingelheim Pharmaceuticals, Inc.
- 当前专利权人： Boehringer Ingelheim Pharmaceuticals, Inc.
- 当前专利权人地址： US CT Ridgefield
- 主分类号： A61K31/4184
- IPC分类号： A61K31/4184 ; A61K39/00 ; A61P1/04 ; A61P3/10 ; A61P11/00 ; A61P11/06 ; A61P11/08 ; A61P17/00 ; A61P17/06 ; A61P25/00 ; A61P27/02 ; A61P27/16 ; A61P29/00 ; A61P35/00 ; A61P37/02 ; A61P37/08 ; A61P43/00 ; C07D235/28 ; C07D235/30 ; C07D409/12 ; C07D43/02
摘要：
Disclosed are substituted benzimidazole compounds of formula (I): wherein R1, R2, R3, R4 and Xa are defined herein. The compounds of the invention inhibit Itk kinase and are therefore useful for treating diseases and pathological conditions involving inflammation, immunological disorders and allergic disorders. Also disclosed are processes for preparing these compounds and to pharmaceutical compositions comprising these compounds.
公开/授权文献
- US07138420B2 Substituted benzimidazole compounds 公开/授权日：2006-11-21