发明申请
- 专利标题： Tec kinase inhibitors
- 专利标题（中）： Tec激酶抑制剂
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申请号： US11055798申请日： 2005-02-09
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公开(公告)号： US20050209284A1公开(公告)日： 2005-09-22
- 发明人: Joerg Bentzien , Brian Cook , Xiang Li , Ho Lo , Chuk Man , Ingo Mugge , Peter Nemoto , Steven Pullen , Doris Riether , Gregory Roth , Fariba Soleymanzadeh , Hidenori Takahashi , Ji Wang , Andre White , Renee Zindell
- 申请人： Joerg Bentzien , Brian Cook , Xiang Li , Ho Lo , Chuk Man , Ingo Mugge , Peter Nemoto , Steven Pullen , Doris Riether , Gregory Roth , Fariba Soleymanzadeh , Hidenori Takahashi , Ji Wang , Andre White , Renee Zindell
- 申请人地址： US CT Ridgefield
- 专利权人： Boehringer Ingelheim Pharmaceuticals, Inc.
- 当前专利权人： Boehringer Ingelheim Pharmaceuticals, Inc.
- 当前专利权人地址： US CT Ridgefield
- 主分类号： A61K31/4184
- IPC分类号： A61K31/4184 ; A61K31/422 ; A61K31/427 ; A61K31/4439 ; C07D235/30 ; C07D401/14 ; C07D409/12 ; C07D409/14 ; C07D413/02 ; C07D413/12 ; C07D413/14 ; C07D417/02 ; C07D417/14 ; C07D491/10 ; C07D43/02
摘要：
Disclosed are compounds of formula(I): wherein Ar1, Ar2, R1, R2, R3, R4 and Xa are defined herein. The compounds of the invention inhibit Itk kinase and are therefore useful for treating diseases and pathological conditions involving inflammation, immunological disorders and allergic disorders. Also disclosed are processes for preparing these compounds and to pharmaceutical compositions comprising these compounds.
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