A method for managing a service flow of a mobile subscriber station (MSS) in a serving base station (BS) for a mobile communication system including the serving BS in communication with the MSS through a wireless access channel, and at least one active BS included in an active BS set of the MSS. Upon receiving a service flow management request from the MSS, the serving BS updates a service flow with the MSS, and transmits the updated service flow to the active BS using a predetermined message. Upon receiving a response message for the updated service flow from the active BS, the serving BS transmits service flow information of each active BS included in the response message to the MSS.