Invention Application
US20050228180A1 Alpha, omega-dicarboximide derivatives as useful uro-selective a1a adrenoceptor blockers
审中-公开
α，ω-二羧酰亚胺衍生物作为有用的泌尿选择性α1肾上腺素受体阻断剂
- Patent Title: Alpha, omega-dicarboximide derivatives as useful uro-selective a1a adrenoceptor blockers
- Patent Title (中): α，ω-二羧酰亚胺衍生物作为有用的泌尿选择性α1肾上腺素受体阻断剂
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Application No.: US10510362Application Date: 2002-04-08
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Publication No.: US20050228180A1Publication Date: 2005-10-13
- Inventor: Mohammad Salman , Gyan Yadav , Somesh Sharma , Gobind Kapkoti , Anita Chugh , Jang Gupta , Nitya Anand
- Applicant: Mohammad Salman , Gyan Yadav , Somesh Sharma , Gobind Kapkoti , Anita Chugh , Jang Gupta , Nitya Anand
- International Application: PCT/IB02/01113 WO 20020408
- Main IPC: C07D241/08
- IPC: C07D241/08 ; A61K31/496 ; A61P13/08 ; A61P35/00 ; A61P43/00 ; C07D209/48 ; C07D211/88 ; C07D403/06 ; C07D491/04 ; C07D43/02
Abstract:
Novel α,β-dicarboximide derivatives which selectively inhibit binding to the α-,1A? adrenergic receptor, a receptor which has been shown to be important in the treatment of benign prostatic hyperplasia. The compounds of the present invention are potentially useful in the treatment of benign prostatic hyperplasia.
Abstract(Chinese):
新型α，β-二羧酰亚胺衍生物，其选择性地抑制与α-，1A？ 肾上腺素能受体，已被证明在治疗良性前列腺增生中是重要的受体。 本发明的化合物可用于治疗良性前列腺增生。
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