Invention Application
US20050234095A1 Indazoles, benzothiazoles, benzoisothiazoles, benzisoxazoles, and preparation and uses thereof
审中-公开
吲唑，苯并噻唑，苯并异噻唑，苯并异恶唑及其制备和用途
- Patent Title: Indazoles, benzothiazoles, benzoisothiazoles, benzisoxazoles, and preparation and uses thereof
- Patent Title (中): 吲唑，苯并噻唑，苯并异噻唑，苯并异恶唑及其制备和用途
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Application No.: US11089533Application Date: 2005-03-25
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Publication No.: US20050234095A1Publication Date: 2005-10-20
- Inventor: Wenge Xie , Brian Herbert , Richard Schumacher , Truc Nguyen , Jianguo Ma , Carla Gauss , Ashok Tehim
- Applicant: Wenge Xie , Brian Herbert , Richard Schumacher , Truc Nguyen , Jianguo Ma , Carla Gauss , Ashok Tehim
- Main IPC: A61K31/439
- IPC: A61K31/439 ; A61K31/4745 ; C07D453/02
Abstract:
The present invention relates generally to the field of ligands for nicotinic acetylcholine receptors (nACh receptors), activation of nACh receptors, and the treatment of disease conditions associated with defective or malfunctioning nicotinic acetylcholine receptors, especially of the brain. Further, this invention relates to novel compounds (e.g., indazoles and benzothiazoles), which act as ligands for the α7 nACh receptor subtype, methods of preparing such compounds, compositions containing such compounds, and methods of use thereof.
Information query
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