发明申请
US20050234095A1 Indazoles, benzothiazoles, benzoisothiazoles, benzisoxazoles, and preparation and uses thereof
审中-公开
吲唑，苯并噻唑，苯并异噻唑，苯并异恶唑及其制备和用途
- 专利标题： Indazoles, benzothiazoles, benzoisothiazoles, benzisoxazoles, and preparation and uses thereof
- 专利标题（中）： 吲唑，苯并噻唑，苯并异噻唑，苯并异恶唑及其制备和用途
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申请号： US11089533申请日： 2005-03-25
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公开(公告)号： US20050234095A1公开(公告)日： 2005-10-20
- 发明人: Wenge Xie , Brian Herbert , Richard Schumacher , Truc Nguyen , Jianguo Ma , Carla Gauss , Ashok Tehim
- 申请人： Wenge Xie , Brian Herbert , Richard Schumacher , Truc Nguyen , Jianguo Ma , Carla Gauss , Ashok Tehim
- 主分类号： A61K31/439
- IPC分类号： A61K31/439 ; A61K31/4745 ; C07D453/02
摘要：
The present invention relates generally to the field of ligands for nicotinic acetylcholine receptors (nACh receptors), activation of nACh receptors, and the treatment of disease conditions associated with defective or malfunctioning nicotinic acetylcholine receptors, especially of the brain. Further, this invention relates to novel compounds (e.g., indazoles and benzothiazoles), which act as ligands for the α7 nACh receptor subtype, methods of preparing such compounds, compositions containing such compounds, and methods of use thereof.
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