发明申请
- 专利标题： Substituted 5-membered polycyclic compounds useful for selective inhibition of the coagulation cascade
- 专利标题（中）： 用于选择性抑制凝血级联的5元多环化合物
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申请号： US11159684申请日： 2005-06-23
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公开(公告)号： US20050239860A1公开(公告)日： 2005-10-27
- 发明人: Michael South , Ronald Webber , Horng-Chih Huang , Mihaly Toth , Alan Moormann , Jeffery Snyder , Jeffrey Scholten , Danny Garland , Melvin Rueppel , William Neumann , Scott Long , Wei Huang , John Trujillo , John Parlow , Darin Jones , Brenda Case , Michael Hayes
- 申请人： Michael South , Ronald Webber , Horng-Chih Huang , Mihaly Toth , Alan Moormann , Jeffery Snyder , Jeffrey Scholten , Danny Garland , Melvin Rueppel , William Neumann , Scott Long , Wei Huang , John Trujillo , John Parlow , Darin Jones , Brenda Case , Michael Hayes
- 申请人地址： US MO St. Louis
- 专利权人： Pharmacia Corporation
- 当前专利权人： Pharmacia Corporation
- 当前专利权人地址： US MO St. Louis
- 主分类号： A61K31/166
- IPC分类号： A61K31/166 ; A61K31/341 ; A61K31/381 ; A61K31/40 ; A61K31/415 ; A61K31/4152 ; A61K31/4168 ; A61K31/4196 ; A61K31/421 ; A61K31/426 ; A61P7/02 ; A61P9/00 ; A61P11/00 ; A61P35/00 ; A61P43/00 ; C07C257/18 ; C07D207/14 ; C07D207/32 ; C07D207/34 ; C07D207/46 ; C07D211/56 ; C07D211/98 ; C07D213/74 ; C07D231/12 ; C07D231/38 ; C07D231/46 ; C07D231/48 ; C07D233/88 ; C07D237/04 ; C07D239/10 ; C07D239/22 ; C07D241/04 ; C07D241/20 ; C07D249/08 ; C07D249/14 ; C07D253/06 ; C07D253/075 ; C07D263/48 ; C07D265/02 ; C07D277/20 ; C07D277/42 ; C07D307/22 ; C07D333/36 ; C07D401/12 ; C07D403/10 ; C07D413/12 ; C07D471/04 ; C07D231/44
摘要：
The present invention relates to compounds, and prodrugs thereof, compositions and methods useful for preventing and treating thrombotic conditions in mammals. The compounds of the present invention, and prodrugs thereof, selectively inhibit certain proteases of the coagulation cascade.
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