Invention Application
- Patent Title: Synthesis of boronic ester and acid compounds
- Patent Title (中): 硼酸酯和酸化合物的合成
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Application No.: US11088667Application Date: 2005-03-24
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Publication No.: US20050240047A1Publication Date: 2005-10-27
- Inventor: I. Pickersgill , John Bishop , Christoph Koellner , Jean-Marc Gomez , Achim Geiser , Robert Hett , Vince Ammoscato , Stephen Munk , Young Lo , Fang-Ting Chiu , Vithalanand Kulkarni
- Applicant: I. Pickersgill , John Bishop , Christoph Koellner , Jean-Marc Gomez , Achim Geiser , Robert Hett , Vince Ammoscato , Stephen Munk , Young Lo , Fang-Ting Chiu , Vithalanand Kulkarni
- Applicant Address: US MA Cambridge
- Assignee: Millennium Pharmaceuticals, Inc.
- Current Assignee: Millennium Pharmaceuticals, Inc.
- Current Assignee Address: US MA Cambridge
- Main IPC: C07F5/02
- IPC: C07F5/02 ; C07F5/04
Abstract:
The invention relates to the synthesis of boronic ester and acid compounds. More particularly, the invention provides improved synthetic processes for the large-scale production of boronic ester and acid compounds, including the peptide boronic acid proteasome inhibitor bortezomib.
Public/Granted literature
- US07714159B2 Synthesis of boronic ester and acid compounds Public/Granted day:2010-05-11
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