发明申请
US20050250945A1 Triazine compounds as inhibitors of bacterial type III protein secretion systems
审中-公开
三嗪化合物作为细菌III型蛋白分泌系统的抑制剂
- 专利标题： Triazine compounds as inhibitors of bacterial type III protein secretion systems
- 专利标题（中）： 三嗪化合物作为细菌III型蛋白分泌系统的抑制剂
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申请号： US11124009申请日： 2005-05-06
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公开(公告)号： US20050250945A1公开(公告)日： 2005-11-10
- 发明人: Xiaobing Li , Fu-An Kang , Mark Macielag
- 申请人： Xiaobing Li , Fu-An Kang , Mark Macielag
- 主分类号： C07D251/18
- IPC分类号： C07D251/18 ; C07D401/04 ; C07D401/12 ; C07D405/04 ; C07D43/02
摘要：
In accordance with the present invention, compounds that inhibit Type III protein section have been identified, and methods for their use provided. In one aspect of the invention, compounds useful in the inhibition of Type III protein section and/or in the treatment and prevention of bacterial infections, particularly Gram-negative bacterial infections, are provided. In another aspect of the invention, methods are provided for the inhibition of Type III protein secretion and/or the treatment and prevention of bacterial infections, particularly Gram-negative bacterial infections using the compounds of the invention.
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